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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TLK2
All Species:
31.52
Human Site:
Y515
Identified Species:
69.33
UniProt:
Q86UE8
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86UE8
NP_001106178.1
772
87661
Y515
H
K
H
A
C
R
E
Y
R
I
H
K
E
L
D
Chimpanzee
Pan troglodytes
XP_523598
848
95816
Y591
H
K
H
A
C
R
E
Y
R
I
H
K
E
L
D
Rhesus Macaque
Macaca mulatta
XP_001107302
907
100501
Y650
H
K
H
A
C
R
E
Y
R
I
H
K
E
L
D
Dog
Lupus familis
XP_548038
918
102784
Y661
H
K
H
A
C
R
E
Y
R
I
H
K
E
L
D
Cat
Felis silvestris
Mouse
Mus musculus
O55047
718
82242
Y461
H
K
H
A
C
R
E
Y
R
I
H
K
E
L
D
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515053
718
81881
Y461
H
K
H
A
C
R
E
Y
R
I
H
K
E
L
D
Chicken
Gallus gallus
XP_418070
750
85456
Y493
H
K
H
A
C
R
E
Y
R
I
H
K
E
L
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q1ECX4
697
79286
I443
H
A
C
R
E
Y
R
I
H
K
E
L
D
H
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_624065
793
90042
Y522
I
K
H
A
L
R
E
Y
N
I
H
K
A
L
D
Nematode Worm
Caenorhab. elegans
P34314
965
109255
K704
V
K
H
A
M
R
E
K
D
I
H
K
S
L
D
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39238
688
78131
Y434
Y
D
L
V
D
H
R
Y
V
A
C
K
L
H
G
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
88.3
82.3
81.2
N.A.
92.4
N.A.
N.A.
68.6
94.1
N.A.
77.9
N.A.
N.A.
47.9
36.5
N.A.
Protein Similarity:
100
88.3
83
81.3
N.A.
92.7
N.A.
N.A.
77.7
95.8
N.A.
83.9
N.A.
N.A.
63.4
50.1
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
N.A.
N.A.
100
100
N.A.
6.6
N.A.
N.A.
73.3
66.6
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
100
100
N.A.
13.3
N.A.
N.A.
73.3
66.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
35.3
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
50.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
0
82
0
0
0
0
0
10
0
0
10
0
0
% A
% Cys:
0
0
10
0
64
0
0
0
0
0
10
0
0
0
0
% C
% Asp:
0
10
0
0
10
0
0
0
10
0
0
0
10
0
82
% D
% Glu:
0
0
0
0
10
0
82
0
0
0
10
0
64
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% G
% His:
73
0
82
0
0
10
0
0
10
0
82
0
0
19
0
% H
% Ile:
10
0
0
0
0
0
0
10
0
82
0
0
0
0
0
% I
% Lys:
0
82
0
0
0
0
0
10
0
10
0
91
0
0
0
% K
% Leu:
0
0
10
0
10
0
0
0
0
0
0
10
10
82
0
% L
% Met:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
10
0
82
19
0
64
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
10
0
0
10
0
0
0
0
10
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
10
0
82
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _